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1

Deletion of a Pathogenic Mutation-Containing Exon of COL7A1 Allows Clonal Gene Editing Correction of RDEB Patient Epidermal Stem Cells

Mencía, Ángeles, Chamorro, Cristina, Bonafont, Jose, Duarte, Blanca, Holguin, Almudena, Illera, Nuria, Llames, Sara G., Escámez, Maria José, Hausser, Ingrid, Del Río, Marcela, Larcher, Fernando, Muril

Journal:

Molecular Therapy — Nucleic Acids

Year:

2018

Language:

english

File:

PDF, 2.28 MB

english, 2018

2

Gene Editing for the Efficient Correction of a Recurrent COL7A1 Mutation in Recessive Dystrophic Epidermolysis Bullosa Keratinocytes

Chamorro, Cristina, Mencía, Angeles, Almarza, David, Duarte, Blanca, Büning, Hildegard, Sallach, Jessica, Hausser, Ingrid, Del Río, Marcela, Larcher, Fernando, Murillas, Rodolfo

Journal:

Molecular Therapy — Nucleic Acids

Year:

2016

Language:

english

File:

PDF, 3.95 MB

english, 2016

3

COL7A1 editing via CRISPR/Cas9 in recessive dystrophic epidermolysis bullosa

Hainzl, Stefan, Peking, Patricia, Kocher, Thomas, Murauer, Eva M., Larcher, Fernando, Del Rio, Marcela, Duarte, Blanca, Steiner, Markus, Klausegger, Alfred, Bauer, Johann W., Reichelt, Julia, Koller,

Journal:

Molecular Therapy

Year:

2017

Language:

english

File:

PDF, 2.72 MB

english, 2017

4

La terapia génica ante el nuevo milenio

Larcher, Fernando, Del Río, Marcela, García, Marta, Muñoz, Marta, García Barreno, Pedro, Jorcano Noval, José L.

Journal:

Year:

2001

File:

PDF, 2.84 MB

2001

5

Advanced Statistical Techniques for Non-Invasive Hyperglycemic States Detection in mice using Millimeter-wave Spectroscopy

Moreno-Oyervides, Aldo, Aguilera-Morillo, M. Carmen, Larcher, Fernando, Krozer, Viktor, Acedo, Pablo

Journal:

IEEE Transactions on Terahertz Science and Technology

Year:

2020

File:

PDF, 5.44 MB

2020

6

A Preclinical Model for the Analysis of Genetically Modified Human Skin In Vivo

Del Rio, Marcela, Larcher, Fernando, Serrano, Fernando, Meana, Alvaro, Muñoz, Marta, Garcia, Marta, Muñoz, Evangelina, Martin, Clara, Bernad, Antonio, Jorcano, José Luis

Journal:

Human Gene Therapy

Year:

2002

Language:

english

File:

PDF, 1.40 MB

english, 2002

7

Aberrant expression of the simple epithelial type II keratin 8 by mouse skin carcinomas but not papillomas

Fernando Larcher, Cristina Bauluz, Margarita Diaz-Guerra, Miguel Quintanilla, Claudio J. Conti, Claudio Ballestin, José L. Jorcano

Journal:

Molecular Carcinogenesis

Year:

1992

Language:

english

File:

PDF, 1.02 MB

english, 1992

8

Clinical Results of an Autologous Engineered Skin

Sara Llames, Eva García, Verónica García, Marcela del Río, Fernando Larcher, Jose Luis Jorcano, Eva López, Purificación Holguín, Francisca Miralles, Jesús Otero, Alvaro Meana

Journal:

Cell and Tissue Banking

Year:

2006

Language:

english

File:

PDF, 315 KB

english, 2006

9

Human embryonic stem-cell derivatives for full reconstruction of the pluristratified epidermis: a preclinical study

Hind Guenou, Xavier Nissan, Fernando Larcher, Jessica Feteira, Gilles Lemaitre, Manoubia Saidani, Marcela Del Rio, Christine C Barrault, François-Xavier Bernard, Marc Peschanski, Christine Baldeschi,

Journal:

Year:

2009

Language:

english

File:

PDF, 1.39 MB

english, 2009

10

Long-Term Survival of Type XVII Collagen Revertant Cells in an Animal Model of Revertant Cell Therapy

Gostyński, Antoni, Llames, Sara, García, Marta, Escamez, María J, Martinez-Santamaria, Lucía, Nijenhuis, Miranda, Meana, Alvaro, Pas, Hendri H, Larcher, Fernando, Pasmooij, Anna M G, Jonkman, Marcel F

Journal:

The Journal of Investigative Dermatology

Year:

2014

Language:

english

File:

PDF, 11.77 MB

english, 2014

11

Correction of Recessive Dystrophic Epidermolysis Bullosa by Transposon-Mediated Integration of COL7A1 in Transplantable Patient-Derived Primary Keratinocytes

Latella, Maria Carmela, Cocchiarella, Fabienne, De Rosa, Laura, Turchiano, Giandomenico, Gonçalves, Manuel A.F.V., Larcher, Fernando, De Luca, Michele, Recchia, Alessandra

Journal:

The Journal of Investigative Dermatology

Year:

2017

Language:

english

File:

PDF, 1.89 MB

english, 2017

12

Role of thrombin in the proliferative response of T-47D mammary tumor cells: Mitogenic action and pleiotropic modifications induced together with epidermal growth factor and insulin

Estela E. Medrano, Eduardo G.A. Cafferata, Fernando Larcher

Journal:

Experimental Cell Research

Year:

1987

Language:

english

File:

PDF, 3.47 MB

english, 1987

13

860. Sustained Long-Term In Vivo Expression of Human Factor IX from Keratinocytes Transduced with HIV-Based Vectors

Escarti-Nebot, Angeles, Serrano, Fernando, del Rio, Marcela, Larcher, Fernando, Bernad, Antonio

Journal:

Molecular Therapy

Year:

2006

Language:

english

File:

PDF, 91 KB

english, 2006

14

Expression of Cyclin D1 in Epithelial Tissues of Transgenic Mice Results in Epidermal Hyperproliferation and Severe Thymic Hyperplasia

Ana I. Robles, Fernando Larcher, Robert B. Whalin, Rodolfo Murillas, Ellen Richie, Irma B. Gimenez-Conti, Jose L. Jorcano and Claudio J. Conti

Journal:

Proceedings of the National Academy of Sciences

Year:

1996

Language:

english

File:

PDF, 1.14 MB

english, 1996

15

Tumor initiation by skin Ha -ras -ment

Guerrero-Aspizua, Sara, Larcher, Fernando, Del Río, Marcela, Jorcano, José L., Conti, Claudio J.

Journal:

Experimental Dermatology

Year:

2015

Language:

english

File:

PDF, 169 KB

english, 2015

16

Correction of Laminin-5 Deficiency in Human Epidermal Stem Cells by Transcriptionally Targeted Lentiviral Vectors

Di Nunzio, Francesca, Maruggi, Giulietta, Ferrari, Stefano, Di Iorio, Enzo, Poletti, Valentina, Garcia, Marta, Del Rio, Marcela, De Luca, Michele, Larcher, Fernando, Pellegrini, Graziella, Mavilio, Fu

Journal:

Molecular Therapy

Year:

2008

Language:

english

File:

PDF, 825 KB

english, 2008

17

Long-term skin regeneration in xenografts from iPSC teratoma-derived human keratinocytes

García, Marta, Quintana-Bustamante, Oscar, Segovia, José C., Bueren, Juan, Martinez-Santamaría, Lucia, Guerrero-Aspizua, Sara, Escamez, María José, Del Rio, Marcela, Larcher, Fernando

Journal:

Experimental Dermatology

Year:

2016

Language:

english

File:

PDF, 610 KB

english, 2016

18

Sequential trisomization of chromosomes 6 and 7 in mouse skin premalignant lesions

C. Marcelo Aldaz, David Trono, Fernando Larcher, Thomas J. Slaga, Claudio J. Conti

Journal:

Molecular Carcinogenesis

Year:

1989

Language:

english

File:

PDF, 581 KB

english, 1989

19

Remote diffuse reflectance spectroscopy sensor for tissue engineering monitoring based on blind signal separation

Martín-Mateos, Pedro, Crespo-Garcia, Sergio, Ruiz-Llata, Marta, Lopez-Fernandez, José Ramón, Jorcano, José Luis, Del Rio, Marcela, Larcher, Fernando, Acedo, Pablo

Journal:

Biomedical Optics Express

Year:

2014

Language:

english

File:

PDF, 1.33 MB

english, 2014

20

Robotic transperitoneal partial nephrectomy in the management of cystic renal cell masses: Outcomes of a multicenter study

Mottrie, A., Challacombe, B., Montorsi, F., Ploumidis, A., Canda, A.E., Larcher, A., Ener, K., De Luyk, N., Buffi, N., Guazzoni, G., Fernando, A., Cestari, A., Catterwell, R., Pappas, A.

Journal:

European Urology Supplements

Year:

2018

Language:

english

File:

PDF, 71 KB

english, 2018

21

Efficient CRISPR-Cas9-Mediated Gene Ablation in Human Keratinocytes to Recapitulate Genodermatoses: Modeling of Netherton Syndrome

GÃ¡lvez, Victoria, ChacÃ³n-Solano, Esteban, Bonafont, Jose, MencÃa, Ãngeles, Di, Wei-Li, Murillas, Rodolfo, Llames, Sara, Vicente, AsunciÃ³n, Del Rio, Marcela, Carretero, Marta, Larcher, Fernando

Journal:

Molecular Therapy — Methods & Clinical Development

Year:

2020

File:

PDF, 4.38 MB

2020

22

Feeder Layer Cell Actions and Applications

Llames, Sara, García-Pérez, Eva, Meana, Álvaro, Larcher, Fernando, del Río, Marcela

Journal:

Tissue Engineering Part B Reviews

Year:

2015

Language:

english

File:

PDF, 465 KB

english, 2015

23

Development of Skin-Humanized Mouse Models of Pachyonychia Congenita

García, Marta, Larcher, Fernando, Hickerson, Robyn P, Baselga, Eulalia, Leachman, Sancy A, Kaspar, Roger L, Del Rio, Marcela

Journal:

The Journal of Investigative Dermatology

Year:

2011

Language:

english

File:

PDF, 3.26 MB

english, 2011

24

Targeted Overexpression of Leptin to Keratinocytes in Transgenic Mice Results in Lack of Skin Phenotype but Induction of Early Leptin Resistance

Rico, Laura, Del Rio, Marcela, Bravo, Ana, Ramirez, Angel, Jorcano, José L., Page, M. Angustias, Larcher, Fernando

Journal:

Year:

2005

Language:

english

File:

PDF, 895 KB

english, 2005

25

Tissue-Engineered Oral Mucosa for Mucosal Reconstruction in a Pediatric Patient With Hemifacial Microsomia and Ankyloglossia

Llames, Sara, Recuero, Ignacio, Romance, Ana, García, Eva, Peña, Ignacio, del Valle, Álvaro Fernández, Meana, Álvaro, Larcher, Fernando, del Río, Marcela

Journal:

The Cleft Palate-Craniofacial Journal

Year:

2014

Language:

english

File:

PDF, 353 KB

english, 2014

26

VEGF/VPF overexpression in skin of transgenic mice induces angiogenesis, vascular hyperpermeability and accelerated tumor development

Larcher, Fernando, Murillas, Rodolfo, Bolontrade, Marcela, Conti, Claudio J, Jorcano, José L

Journal:

Year:

1998

Language:

english

File:

PDF, 1.28 MB

english, 1998

27

A 5'-Upstream Region of a Bovine Keratin 6 Gene Confers Tissue-Specific Expression and Hyperproliferation-Related Induction in Transgenic Mice

Angel Ramirez, Miguel Vidal, Ana Bravo, Fernando Larcher and Jose L. Jorcano

Journal:

Proceedings of the National Academy of Sciences

Year:

1995

Language:

english

File:

PDF, 1.33 MB

english, 1995

28

Increased secretory activity and estradiol receptor expression are among other relevant aspects of MCF-7 human breast tumor cell growth which are expressed only in the absence of serum

Estela E. Medrano, Mariana Resnicoff, Eduardo G.A. Cafferata, Fernando Larcher, Osvaldo Podhajcer, Laura Bover, Beatriz Molinari

Journal:

Experimental Cell Research

Year:

1990

Language:

english

File:

PDF, 3.55 MB

english, 1990

29

Long-term Engraftment of Single Genetically Modified Human Epidermal Holoclones Enables Safety Pre-assessment of Cutaneous Gene Therapy

Larcher, Fernando, Dellambra, Elena, Rico, Laura, Bondanza, Sergio, Murillas, Rodolfo, Cattoglio, Claudia, Mavilio, Fulvio, Jorcano, José L, Zambruno, Giovanna, Del Rio, Marcela

Journal:

Molecular Therapy

Year:

2007

Language:

english

File:

PDF, 488 KB

english, 2007

30

Recent advances in gene therapy with skin cells

DEL RIO, MARCELA, LARCHER, FERNANDO, JORCANO, JOSÉ LUIS

Journal:

European Review

Year:

2002

Language:

english

File:

PDF, 6.56 MB

english, 2002

31

Topical Enzyme-Replacement Therapy Restores Transglutaminase 1 Activity and Corrects Architecture of Transglutaminase-1-Deficient Skin Grafts

Aufenvenne, Karin, Larcher, Fernando, Hausser, Ingrid, Duarte, Blanca, Oji, Vinzenz, Nikolenko, Heike, Del Rio, Marcela, Dathe, Margitta, Traupe, Heiko

Journal:

The American Journal of Human Genetics

Year:

2013

Language:

english

File:

PDF, 2.13 MB

english, 2013

32

Complexity of VEGF Responses in Skin Carcinogenesis Revealed through Ex Vivo Assays Based on a VEGF-A Null Mouse Keratinocyte Cell Line

Mirones, Isabel, Conti, Claudio J, Martínez, Jesús, Garcia, Marta, Larcher, Fernando

Journal:

The Journal of Investigative Dermatology

Year:

2008

Language:

english

File:

PDF, 4.13 MB

english, 2008

33

125. Engineered Nucleases-Mediated In Situ Correction of a Genetic Defect By Homologous Recombination Into the Native Locus

Carmela Latella, Maria, Miselli, Francesca, Turchiano, Giandomenico, Mussolino, Claudio, Cudeiro, Javier, Larcher, Fernando, Recchia, Alessandra

Journal:

Molecular Therapy

Year:

2015

Language:

english

File:

PDF, 306 KB

english, 2015

34

Classification of skin phenotypes caused by diabetes mellitus using complex scattering parameters in the millimeter-wave frequency range

Dornuf, Fabian, Martín-Mateos, Pedro, Duarte, Blanca, Hils, Bernhard, Bonilla-Manrique, Oscar Elias, Larcher, Fernando, Acedo, Pablo, Krozer, Viktor

Journal:

Scientific Reports

Year:

2017

Language:

english

File:

PDF, 1.36 MB

english, 2017

35

[IEEE 2017 IEEE International Conference on Microwaves, Antennas, Communications and Electronic Systems (COMCAS) - Tel-Aviv (2017.11.13-2017.11.15)] 2017 IEEE International Conference on Microwaves, Antennas, Communications and Electronic Systems (COMCAS) - Determination of hyperglycemic states in mice using millimeter-wave sensing

Dornuf, Fabian, Martin-Mateos, Pedro, Krozer, Viktor, Acedo, Pablo, Laguzzi, Fernando Larcher

Year:

2017

Language:

english

File:

PDF, 1014 KB

english, 2017

36

Regulation of the differentiation-related gene Drg-1 during mouse skin carcinogenesis

Elena Gómez-Casero, Manuel Navarro, Marcelo L. Rodríguez-Puebla, Fernando Larcher, Jesús M. Paramio, Claudio J. Conti, José L. Jorcano

Journal:

Molecular Carcinogenesis

Year:

2001

Language:

english

File:

PDF, 224 KB

english, 2001

37

Antiproliferative effects of PCA-4230, a new antithrombotic drug, in vascular smooth muscle cells

Marcela Del Rio, Carlos Sunkel, Fernando Larcher, M. Pilar Ortega

Journal:

British Journal of Pharmacology

Year:

1997

Language:

english

File:

PDF, 359 KB

english, 1997

38

Growth inhibitory activity of indapamide on vascular smooth muscle cells

Patricia Ganado, Emilio Ruiz, Marcela Del Rio, Fernando Larcher, Mercedes Sanz, Joern R. Steinert, Teresa Tejerina

Journal:

European Journal of Pharmacology

Year:

2001

Language:

english

File:

PDF, 267 KB

english, 2001

39

Sustained phenotypic reversion of junctional epidermolysis bullosa dog keratinocytes: Establishment of an immunocompetent animal model for cutaneous gene therapy

Flavia Spirito, Annabelle Capt, Marcela Del Rio, Fernando Larcher, Eric Guaguere, Olivier Danos, Guerrino Meneguzzi

Journal:

Biochemical and Biophysical Research Communications

Year:

2006

Language:

english

File:

PDF, 497 KB

english, 2006

40

Modeling normal and pathological processes through skin tissue engineering

Marta Garcia, Maria Jose Escamez, Marta Carretero, Isabel Mirones, Lucia Martinez-Santamaria, Manuel Navarro, Jose L. Jorcano, Alvaro Meana, Marcela Del Rio, Fernando Larcher

Journal:

Molecular Carcinogenesis

Year:

2007

Language:

english

File:

PDF, 173 KB

english, 2007

41

A Comparison of Targeting Performance of Oncoretroviral Versus Lentiviral Vectors on Human Keratinocytes

Serrano, Fernando, Del Rio, Marcela, Larcher, Fernando, Garcia, Marta, Muñoz, Evangelina, Escamez, María José, Muñoz, Marta, Meana, Alvaro, Bernad, Antonio, Jorcano, José Luis

Journal:

Human Gene Therapy

Year:

2003

Language:

english

File:

PDF, 616 KB

english, 2003

42

Human plasma as a dermal scaffold for the generation of a completely autologous bioengineered skin

Llames, Sara G., Del Rio, Marcela, Larcher, Fernando, García, Eva, García, Marta, José Escamez, María, Jorcano, Jose L., Holguín, Purificación, Meana, Alvaro

Journal:

Transplantation Journal

Year:

2004

Language:

english

File:

PDF, 1.26 MB

english, 2004

43

[IEEE 2017 42nd International Conference on Infrared, Millimeter, and Terahertz Waves (IRMMW-THz) - Cancun, Mexico (2017.8.27-2017.9.1)] 2017 42nd International Conference on Infrared, Millimeter, and Terahertz Waves (IRMMW-THz) - Monitoring the evolution of hyperglycemia in mice using mm-wave spectroscopy

Martin-Mateos, Pedro, Moreno-Oyervides, Aldo, Ulisse, Giacomo, Duarte, Blanca, Dornuf, Fabian, Larcher, Fernando, Krozer, Viktor, Acedo, Pablo

Year:

2017

Language:

english

File:

PDF, 285 KB

english, 2017

44

Construction of Skin Equivalents for Gene Therapy of Recessive Dystrophic Epidermolysis Bullosa

Gache, Yannick, Baldeschi, Christine, Del Rio, Marcela, Gagnoux-Palacios, Laurent, larcher, Fernando, Lacour, Jean-Philippe, Meneguzzi, Guerrino

Journal:

Human Gene Therapy

Year:

2004

Language:

english

File:

PDF, 402 KB

english, 2004

45

[OSA Biomedical Optics - Miami, Florida, (2014..-..)] Biomedical Optics 2014 - Portable, Non-contact, Diffuse Reflectance Spectroscopy System for Early Skin Implants Assessment

Martín-Mateos, Pedro, Crespo-Garcia, Sergio, Ruiz-Llata, Marta, Lopez-Fernandez, José Ramón, Jorcano, José Luis, Del Rio, Marcela, Larcher, Fernando, Acedo, Pablo

Year:

2014

Language:

english

File:

PDF, 122 KB

english, 2014

46

In Vivo Assessment of Acute UVB Responses in Normal and Xeroderma Pigmentosum (XP-C) Skin-Humanized Mouse Models

Marta García, Sara Llames, Eva García, Alvaro Meana, Natividad Cuadrado, Mar Recasens, Susana Puig, Eduardo Nagore, Nuria Illera, José Luis Jorcano, Marcela Del Rio, Fernando Larcher

Journal:

The American Journal of Pathology

Year:

2010

Language:

english

File:

PDF, 1.31 MB

english, 2010

47

Long-Term Skin Regeneration From a Gene-Targeted Human Epidermal Stem Cell Clone

Duarte, Blanca, Miselli, Francesca, Murillas, Rodolfo, Espinosa-Hevia, Luis, Cigudosa, Juan Cruz, Recchia, Alessandra, Del Río, Marcela, Larcher, Fernando

Journal:

Molecular Therapy

Year:

2014

Language:

english

File:

PDF, 125 KB

english, 2014

48

[IEEE 2018 48th European Microwave Conference (EuMC) - Madrid, Spain (2018.9.23-2018.9.27)] 2018 48th European Microwave Conference (EuMC) - Non-invasive Detection and Monitoring of Sustained Glycemic Fluctuations using Mm-Wave Spectroscopy

Moreno-Overvides, Aldo, Martin-Mateos, Pedro, Aguilera-Morillo, M. Carmen, Ulisse, Giacomo, Larcher, Fernando, Krozer, Viktor, Acedo, Pablo

Year:

2018

Language:

english

File:

PDF, 193 KB

english, 2018

49

An In Vivo Model of Wound Healing in Genetically Modified Skin-Humanized Mice

Escamez, Maria Jose, Garcia, Marta, Larcher, Fernando, Meana, Alvaro, Munoz, Evangelina, Jorcano, Jose Luis, Del Rio, Marcela

Journal:

The Journal of Investigative Dermatology

Year:

2004

Language:

english

File:

PDF, 3.34 MB

english, 2004

50

Augmented expression of cytokines in mouse epidermal tumor cells and its possible involvement in the induction of hematopoietic alterations

Cristina Bauluz, Fernando Larcher, Claudio Ballestin, Teresa Grande, José L. Jorcano

Journal:

Molecular Carcinogenesis

Year:

1994

Language:

english

File:

PDF, 1.02 MB

english, 1994

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